College of Agricultural Sciences

H. Schedel, Quaedflieg, P. J. L. M., Broxterman, Q. B., Bisson, W. H., Duchateau, A. L. L., Maes, I. C. H., Herzschuh, R., and Burger, K., “Synthesis of (R)-4, 4, 4-trifluoro-2-mercaptobutyric acid”, Tetrahedron: Asymmetry, vol. 11, pp. 2125–2131, 2000.

A. Dehner, Planker, E., Gemmecker, G., Broxterman, Q. B., Bisson, W. H., Formaggio, F., Crisma, M., Toniolo, C., and Kessler, H., “Solution Structure, Dimerization, and Dynamics of a Lipophilic $\alpha$/310-Helical, C$\alpha$-Methylated Peptide. Implications for Folding of Membrane Proteins”, Journal of the American Chemical Society, vol. 123, pp. 6678–6686, 2001.

M. Crisma, Bisson, W. H., Formaggio, F., Broxterman, Q. B., and Toniolo, C., “Factors governing 310-helix vs $\alpha$-helix formation in peptides: Percentage of C$\alpha$-tetrasubstituted $\alpha$-amino acid residues and sequence dependence”, Biopolymers, vol. 64, pp. 236–245, 2002.

W. H. Bisson, Scapozza, L., Westera, G., Mu, L., and Schubiger, P. A., “Ligand selectivity for the acetylcholine binding site of the rat $\alpha$4$\beta$2 and $\alpha$3$\beta$4 nicotinic subtypes investigated by molecular docking”, Journal of medicinal chemistry, vol. 48, pp. 5123–5130, 2005.

L. Mu, Drandarov, K., Bisson, W. H., Schibig, A., Wirz, C., P Schubiger, A., and Westera, G., “Synthesis and binding studies of epibatidine analogues as ligands for the nicotinic acetylcholine receptors”, European journal of medicinal chemistry, vol. 41, pp. 640–650, 2006.

W. H. Bisson, Cheltsov, A. V., Bruey-Sedano, N., Lin, B., Chen, J., Goldberger, N., May, L. T., Christopoulos, A., Dalton, J. T., Sexton, P. M., and , “Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs”, Proceedings of the National Academy of Sciences, vol. 104, pp. 11927–11932, 2007.

S. Raduner, Bisson, W. H., Abagyan, R., Altmann, K. - H., and Gertsch, J., “Self-assembling cannabinomimetics: supramolecular structures of N-alkyl amides”, Journal of natural products, vol. 70, pp. 1010–1015, 2007.

W. H. Bisson, Zhang, Z., Welsh, K., Huang, J. - W., Ryan, J., Reed, J. C., and Pellecchia, M., “Binding Properties of the C-terminal Domain of VIAF”, Chemical biology & drug design, vol. 72, pp. 331–336, 2008.

W. H. Bisson, Westera, G., P Schubiger, A., and Scapozza, L., “Homology modeling and dynamics of the extracellular domain of rat and human neuronal nicotinic acetylcholine receptor subtypes $\alpha$4$\beta$2 and $\alpha$7”, Journal of molecular modeling, vol. 14, pp. 891–899, 2008.

W. H. Bisson, Abagyan, R., and Cavasotto, C. N., “Molecular basis of agonicity and antagonicity in the androgen receptor studied by molecular dynamics simulations”, Journal of Molecular Graphics and Modelling, vol. 27, no. 4, pp. 452 - 458, 2008.

H. Nian, Bisson, W. H., Dashwood, W. - M., Pinto, J. T., and Dashwood, R. H., “$\alpha$-Keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells”, Carcinogenesis, vol. 30, pp. 1416–1423, 2009.

J. - I. Lee, Nian, H., Cooper, A. J. L., Sinha, R., Dai, J., Bisson, W. H., Dashwood, R. H., and Pinto, J. T., “ -Keto Acid Metabolites of Naturally Occurring Organoselenium Compounds as Inhibitors of Histone Deacetylase in Human Prostate Cancer Cells”, Cancer Prevention Research, vol. 2, no. 7, pp. 683 - 693, 2009.

W. H. Bisson, Koch, D. C., O'Donnell, E. F., Khalil, S. M., Kerkvliet, N. I., Tanguay, R. L., Abagyan, R., and Kolluri, S. Kumar, “Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands”, Journal of medicinal chemistry, vol. 52, pp. 5635–5641, 2009.

W. H. Bisson, Koch, D. C., Donnell, E. F. ’, Khalil, S. M., Kerkvliet, N. I., Tanguay, R. L., Abagyan, R., and Kolluri, S., “Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands”, Journal of Medicinal Chemistry, vol. 52, no. 18, pp. 5635 - 5641, 2009.

W. H. Bisson, Koch, D. C., O'Donnell, E. F., Khalil, S. M., Kerkvliet, N. I., Tanguay, R. L., Abagyan, R., and Kolluri, S. Kumar, “Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands.”, J Med Chem, vol. 52, no. 18, pp. 5635-41, 2009.

C. A. Larsen, Bisson, W. H., and Dashwood, R. H., “Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies”, Journal of medicinal chemistry, vol. 52, pp. 6543–6545, 2009.

E. F. O'Donnell, Saili, K. S., Koch, D. C., Kopparapu, P. R., Farrer, D., Bisson, W. H., Mathew, L. K., Sengupta, S., Kerkvliet, N. I., Tanguay, R., and , “The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor”, PLoS One, vol. 5, p. e13128, 2010.

E. F. O'Donnell, Saili, K. S., Koch, D. C., Kopparapu, P. R., Farrer, D., Bisson, W. H., Mathew, L. K., Sengupta, S., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S. Kumar, “The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor.”, PLoS One, vol. 5, no. 10, 2010.

E. F. O'Donnell, Saili, K. S., Koch, D. C., Kopparapu, P. R., Farrer, D., Bisson, W. H., Mathew, L. K., Sengupta, S., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S., “The Anti-Inflammatory Drug Leflunomide Is an Agonist of the Aryl Hydrocarbon Receptor”, PLoS ONE, vol. 5, no. 10, p. e13128, 2010.

A. D. Benninghoff, Bisson, W. H., Koch, D. C., Ehresman, D. J., Kolluri, S., and Williams, D. E., “Estrogen-like activity of perfluoroalkyl acids in vivo and interaction with human and rainbow trout estrogen receptors in vitro”, Toxicological sciences, p. kfq379, 2010.

J. D. Chavez, Bisson, W. H., and Maier, C. S., “A targeted mass spectrometry-based approach for the identification and characterization of proteins containing $\alpha$-aminoadipic and $\gamma$-glutamic semialdehyde residues”, Analytical and bioanalytical chemistry, vol. 398, pp. 2905–2914, 2010.

C. A. Larsen, Dashwood, R. H., and Bisson, W. H., “Tea catechins as inhibitors of receptor tyrosine kinases: mechanistic insights and human relevance”, Pharmacological Research, vol. 62, pp. 457–464, 2010.

K. J. Smith, Murray, I. A., Tanos, R., Tellew, J., Boitano, A. E., Bisson, W. H., Kolluri, S., Cooke, M. P., and Perdew, G. H., “Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism”, Journal of Pharmacology and Experimental Therapeutics, vol. 338, pp. 318–327, 2011.

J. D. Chavez, Wu, J., Bisson, W. H., and Maier, C. S., “Site-specific proteomic analysis of lipoxidation adducts in cardiac mitochondria reveals chemical diversity of 2-alkenal adduction”, Journal of proteomics, vol. 74, pp. 2417–2429, 2011.

I. A. Murray, Flaveny, C. A., Chiaro, C. R., Sharma, A. K., Tanos, R. S., Schroeder, J. C., Amin, S. G., Bisson, W. H., Kolluri, S., and Perdew, G. H., “Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3′, 4′-dimethoxy-$\alpha$-naphthoflavone”, Molecular pharmacology, vol. 79, pp. 508–519, 2011.